Nasopharyngeal Carcinoma Genes and Survival in Patients with Locoregionally Advanced Polymorphisms in the Endothelin-1 and Endothelin A Receptor
نویسندگان
چکیده
Purpose: We aimed to investigate the prognostic role of endothelin-1 (EDN1) and endothelin A receptor (EDNRA) gene polymorphisms in patients with locoregionally advanced nasopharyngeal carci-
منابع مشابه
Imaging, Diagnosis, Prognosis Polymorphisms in the Endothelin-1 and Endothelin A Receptor Genes and Survival in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma
Purpose: We aimed to investigate the prognostic role of endothelin-1 (EDN1) and endothelin A receptor (EDNRA) gene polymorphisms in patients with locoregionally advanced nasopharyngeal carci-
متن کاملPolymorphisms in the endothelin-1 and endothelin a receptor genes and survival in patients with locoregionally advanced nasopharyngeal carcinoma.
PURPOSE We aimed to investigate the prognostic role of endothelin-1 (EDN1) and endothelin A receptor (EDNRA) gene polymorphisms in patients with locoregionally advanced nasopharyngeal carcinoma (NPC). EXPERIMENTAL DESIGN Two hundred three consecutive patients with locoregionally advanced NPC were enrolled. Seven potentially functional polymorphisms in the EDN1 and EDNRA genes were determined ...
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Background: Heparanase and endothelin-1/endothelin A receptor (ET-1/ETAR) expressions increase in cancer. This condition enhances tumor progression and correlates with poor survival. Limited data are documented regarding the role of heparanase and ET-1/ETAR in epithelial ovarian cancer (EOC). We sought to characterize the correlation between heparanase and ET-1/ETAR in EOC.Methods: Thirty patie...
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Background: Recent research has provided evidences indicating the importance of endothelin axis in carcinogenesis. According to our knowledge, there are little information about endothelin A receptor (ETA) expression in oral squamous cell carcinoma (OSCC). So, the aim of the present study was to evaluate the immunohistochemical expression of ETA in OSCC and normal oral mucosa (...
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Background and purpose: Endothelin axis (endothelin or ET) including endothelin A receptor (ETA) play a major role as the regulator of vessels tone and tissue differentiation and development. There are evidences of the importance of endothelin axis in carcinogenesis. No data exists about comparison of ETA expression between dysplasia and oral squamous cell carcinoma (OSCC). So, the aim of this ...
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